Hey ya'll whats up... Im new here and I am thinking about getting me a bike... I have a friend who is selling a Honda 350 4x4 for a decent price and I wanted to know if that was big enough for lift, tires, and some others to take mud riding???

It's at the smaller end but anything can be lifted.  I have seen smaller ATVs wtih 27" mud tires that do very well.  AC650 has some experience working with some smaller ATVs and should be able to give you some more specific direction.